Why vitamin C is paired with collagen for connective tissue
Vitamin C is a required cofactor for the enzymes that hydroxylate proline and lysine during collagen synthesis, the step that stabilizes the collagen triple helix. The rationale for taking collagen with vitamin C before connective-tissue loading is to supply both the amino-acid building blocks and the cofactor when blood flow to tendons and ligaments is briefly elevated.
Small studies have reported increased markers of collagen synthesis, such as blood levels of a procollagen fragment, after this protocol. These are biochemical signals, not yet proof of faster injury healing or stronger tendons in the long term.
Reading the synthesis-marker findings cautiously
Often-cited protocols use around 15 g of collagen with roughly 50 mg of vitamin C taken about an hour before short, targeted loading. Reports of synthesis markers doubling come from a limited evidence base with small samples, so the practical effect on actual tendon outcomes remains preliminary.
This is general educational information, not medical advice. Tendon and ligament injuries are clinical issues, and supplementation is not a substitute for proper rehabilitation. Consult a qualified professional for any injury management.