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GALT: 70% of Immune Tissue in the Gut

Peyer patches, lamina propria, and IgA-secreting cells form the largest immune organ in the body.

A free, animated galt: 70% of immune tissue in the gut you can read here or embed on any website, from Scrollchart.

GALT: 70% of Immune Tissue in the Gut

GALT: 70% of Immune Tissue in the GutPeyer patches, M cells, and IgA-secreting plasma cells form the body's largest immune organImmuneTissueGALT 70%Bone marrow 15%Spleen 10%Other 5%Body Immune Tissue DistributionSmall Intestinal Wall (Cross-section)LumenMucus layerEpithelium + M cellsPeyer patch / GALTLamina propriamicrobiomeM cells sample antigensfrom lumenPeyer patchB cells + T cells

A donut showing distribution of body immune tissue, with the GALT slice dominant. A second panel zooms into Peyer patches, M cells, and IgA secretion.

Good for

  • Articles explaining gut immunity and why the gut is the body's immune headquarters
  • Medical-educator content on Peyer's patches, M cells, and IgA biology
  • Nutrition writing linking dietary fiber and butyrate to mucosal immune function

Source & accuracy

This galt: 70% of immune tissue in the gut is an editorial illustration built to represent the concept accurately. Where it shows figures, they are typical or representative values chosen to make the relationship clear, not a single underlying dataset. The diagram and its explainer are reviewed and maintained centrally, and updated over time as understanding improves.

What GALT is and where the '70%' figure comes from

Gut-associated lymphoid tissue (GALT) includes Peyer patches in the small intestine, immune cells scattered through the lamina propria, and the plasma cells that secrete secretory IgA into the gut lumen. The often-quoted claim that the gut holds about 70 percent of the body's immune tissue reflects the very large number of immune cells stationed along the digestive tract; the exact percentage is an estimate that varies by how tissue is counted, so it is best treated as 'a large share' rather than a precise constant.

Why so much immunity sits at the gut wall

The gut lining is the body's largest interface with the outside world, constantly exposed to food antigens and trillions of microbes. GALT must do two opposing jobs: tolerate harmless food and commensal bacteria while staying ready to respond to pathogens. Secretory IgA helps by coating and neutralizing microbes without provoking inflammation. This balance, and how diet and the microbiome influence it, is an active area of study.

This is general educational information, not medical advice.

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Reference

What this is
A free, embeddable, animated galt: 70% of immune tissue in the gut for any website.
Who uses it
Nutrition blogs, Medical educators, Biology educators.
How to embed
Copy one line of HTML. No signup. No watermark. Works in WordPress, Webflow, Ghost, Substack, plain HTML.
File size
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License
Free forever. Editorial explainer text included; updated centrally over time.

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Frequently asked questions

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