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Sex Hormone Binding Globulin (SHBG)

SHBG binds testosterone and estradiol, controlling free hormone availability.

A free, animated sex hormone binding globulin (shbg) you can read here or embed on any website, from Scrollchart.

Sex Hormone Binding Globulin (SHBG)

Sex Hormone Binding Globulin (SHBG)Only the 2 percent free fraction signals at the androgen receptorTotal Testosterone600 ng/dLFree: 12 ng/dLWhere does the hormone live?SHBG-bound60 percenttightly bound, biologically inertAlbumin-bound38 percentloosely bound, partly bioavailableFree2 percentbioactive at the receptorSHBG raised by:estrogen, thyroid excess, ageing, fasting, chronic alcohol, liver disease (less free hormone)SHBG lowered by:obesity, insulin resistance, androgens, growth hormone, hypothyroidism (more free hormone)

Donut chart of total testosterone partitioned into SHBG-bound (~60%), albumin-bound (~38%), and free (~2%). Free fraction is the bioactive pool.

Good for

  • Patient-facing explainers on why total testosterone can mislead
  • Articles on insulin resistance, obesity, and low free testosterone
  • Endocrinology teaching on bioavailable hormone calculation

Source & accuracy

This sex hormone binding globulin (shbg) is an editorial illustration built to represent the concept accurately. Where it shows figures, they are typical or representative values chosen to make the relationship clear, not a single underlying dataset. The diagram and its explainer are reviewed and maintained centrally, and updated over time as understanding improves.

The carrier that sets free hormone levels

Sex hormone binding globulin (SHBG) is a protein made mainly by the liver that binds sex steroids in the blood, with a particularly tight grip on testosterone and a weaker hold on estradiol. Hormone bound to SHBG is largely held in reserve, while the small unbound (free) fraction is what is generally considered available to tissues. So SHBG acts as a buffer that influences how much active hormone reaches cells.

Because of this, total testosterone can look normal while free testosterone is altered if SHBG is unusually high or low, which is why clinicians sometimes measure or calculate the free fraction.

What raises and lowers SHBG

SHBG tends to rise with higher estrogen states, thyroid hormone excess, aging in men, and liver-related factors, and to fall with higher insulin levels, obesity, and excess androgens. This means SHBG shifts can change free hormone availability without any change in gland output.

Interpreting SHBG always requires the full clinical picture rather than the number alone. This is general educational information, not medical advice; hormone testing should be interpreted by a qualified professional.

Embed this diagram

Add this animated sex hormone binding globulin (shbg) to your own site. Copy one line of HTML, or use the embed builder for theme and sizing options.

Reference

What this is
A free, embeddable, animated sex hormone binding globulin (shbg) for any website.
Who uses it
Medical educators, Biohacker blogs, Health blogs.
How to embed
Copy one line of HTML. No signup. No watermark. Works in WordPress, Webflow, Ghost, Substack, plain HTML.
File size
iframe embed, ~80 KB gzipped (loads on demand, does not block your page paint).
License
Free forever. Editorial explainer text included; updated centrally over time.

Embed format options

Copy the universal HTML snippet, the WordPress shortcode, or an iframe fallback - see the WordPress plugin page for details. Any format keeps the same Core Web Vitals profile and the same explainer text.

Embed snippet
<div data-scrollchart="sex-hormone-binding-globulin" data-scrollchart-v="1"></div>
<script src="https://scrollchart.com/embed.js" async></script>

Frequently asked questions

Where can I get a free animated "Sex Hormone Binding Globulin (SHBG)" for my website?
Scrollchart provides "Sex Hormone Binding Globulin (SHBG)" as a free, embeddable animated diagram you can add to any website with one line of HTML. No signup is required and there is no watermark. The diagram and its explainer text are served from scrollchart.com, so the embed stays current without any maintenance on your end.
How do I embed a sex hormone binding globulin (shbg) diagram in a health or wellness blog?
Copy the HTML snippet from the Scrollchart diagram page and paste it into any post or page in your CMS. It works in WordPress, Webflow, Ghost, Substack, and plain HTML without any plugin or account. The diagram renders as animated SVG directly in your page, so search engines can index the accompanying explainer text.