What separates these seven stimulants
Caffeine, theacrine, dynamine (methylliberine), synephrine, yohimbine, PEA, and theanine differ less in raw potency than in their kinetics and side-effect profile. Caffeine is the reference point: fast onset, a few hours of duration, well-characterised tolerance. Theacrine and dynamine are caffeine-adjacent purine alkaloids reported to have a smoother feel and, for theacrine, slower tolerance build-up in short studies. Theanine is not a stimulant at all; it is an amino acid added to blunt jitter.
Synephrine and yohimbine act through the adrenergic system rather than adenosine, which is why they show up in fat-loss rather than focus blends. PEA is the outlier: a trace amine with an intense but very short effect that depends heavily on how fast monoamine oxidase clears it.
Reading the onset, jitter, and lipolysis columns together
The matrix scores each ingredient on onset, duration, jitter, tolerance, and lipolysis so they can be compared on the axes that actually matter for a stack. A high lipolysis score (synephrine, yohimbine) does not imply a high focus score, and a low jitter score (theanine, theacrine) does not mean the ingredient drives fat loss. The columns describe different mechanisms, so reading any single row in isolation can mislead.
These scores summarise mostly short-term and preliminary human data, and individual sensitivity, especially to yohimbine's blood-pressure and anxiety effects, varies widely. This is general educational information, not medical advice; consult a qualified professional before combining stimulants, particularly with heart, blood-pressure, or psychiatric conditions.